Stuff not being tested for adequately yet...allowing older claimers to become overnight sensations...
I did cut and paste from another site...thought it should be brought to light...the more exposure the better in my book...
www.usada.org/choose-usada/
These are the types of substances that have found their way to cycling and other endurance sports...
GW1516
A chemical compound by the name of GW156 activated another chemical called PPARD – a chemical responsible for burning fat in mammalian bodies. In the study, Salk researchers gave normal – albeit sedentary – mice a high regular dose of GW for a long period of time, compared to mice that did not. Both were subjected to intense treadmill tests, a rat race if you will, to see how long they could run before they were exhausted.
Mice in the control group ran for about 160 minutes before giving up. Mice on the drug, however, ran for a whopping 270 minutes – more than 70 percent longer. The biochemical processes didn’t change the way a performance enhancing drug might – their blood sugar levels still regulated their natural exhaustion.
FG4592
So how does FG-4592/ASP1517 actually work? In very broad terms, it works at the genetic level to allow the body’s natural red blood cell production to function more efficiently. Or, to quote from a FibroGen press release, FG-4592/ASP1517 is “an inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase”. To understand that statement, we’ll need to return to a couple of principles that we touched on in an earlier article about gene doping.
AICAR
Next, the scientists focused on another protein called AMPK. They gave sedentary mice a daily injection of AICAR, which boosts AMPK, for a month.
At the end of the month, those mice ran 23% longer and 44% farther than before starting AICAR treatment. That is, their endurance had improved without working out.
The results show that AMPK and PPAR-delta "can be targeted by orally active drugs to enhance training or even to increase endurance without exercise," write the researchers
