There was an old DOS program Six Shooter
written by the late Richard Bauer (who used to post on this board)...that did EXACTLY what you have in mind.
I used it for many, many years. The beauty of the program is that it accepted either an odds line, a percentage line, or A, B, C, D ranking. The "gorgeousness" of the program was that the input TRULY reflected the handicapper's feeling about each race instead of "shotgunning" by adding horses in a given race that did not have the same chance of winning as your most favored horse or horses.
Back in those days, you had to actually write out the tickets (pre ADW) which in the amounts we were playing, could add up to a couple/few hundred tickets. Seriously. There obviously was some pressure to mark each ticket without error from human intervention.
The program maxed out at an $8,000 play...four thousand combinations.
Bauer was FAR ahead of his time with that program.
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