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It is not difficult to make a spreadsheet that will calculate how various bet sizes affect payouts in various pool sizes. Then you can come up with a rule of thumb to bet X% of the estimated pool. If you are going to make a spreadsheet make sure you also add your losing bets into the calculation. (if you are boxing three horses you are buying five losing tickets.)
I have done it for myself but I am not going to tell you my conclusions because we likely have very different tolerances for how much our bet depresses the price, due to how many combinations we bet and our win percentage.
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“If you want to outwit the devil, it is extremely important that you don't give him advanced notice."
~Alan Watts
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