https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565486/
quote: Objective
We estimated YLL and productivity loss from SUD in working age adults and compared it with leading causes of death in the United States.
Methods:
We screened all out of hospital deaths among people 20–64 in Wake County, North Carolina from 2013 to 2015 to adjudicate SUDs. We extrapolated Wake County incidence to estimate the age and sex standardized rate of SUD in the United States. YLL was calculated based on the remaining life expectancy of the victims. Incorporating market and housekeeping value estimated the present value of lifetime productivity loss due to SUD.
Results:
SUD incidence rates in the US adults 20–64 were 49.3 (95%CI: 41.2–58.3) and 21.7 (95%CI: 16.5–27.8) per 100000 among men and women, respectively. SUD resulted in the loss of 2 million years of life, accounting for 10.0% of YLL from all causes of death. Among natural causes of death, YLL from SUD was only lower than that from all cancers combined and heart disease. Lifetime productivity loss due to SUD was about $51 billion, exceeding productivity loss from any individual cancer.
