I use Malwarebytes Premium 3.5.1 along with Bitdefender Total Security 2018. They work well together and I don't see any resource hogging. I do have 16 GB of RAM but Process Explorer indicates that MWB is only taking up about 180 MB of that. The only problem that I had was when update to Malwarebytes that caused the web protection to turn itself off, but that got resolved fairly quickly.
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