The amount of emphasis you put on "humans" can certainly have an effect on win percentage. For instance, if two horses look like the two main contenders in a race, both seem about equal talent and fitness, and one is trained by Pletcher and has Johnny V riding and the other is trained by a trainer who has a lifetime win percentage of 8% with an average jockey up, the Pletcher horse has a better chance of winning. But if the Pletcher horse is 6-5 and the other horse is 12-1, the 12-1 shot is still the better bet.
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