LLHorses
02-11-2013, 03:13 PM
Awwww that frog is so cute. :D
http://www.equinechronicle.com/health/milkshakes-snake-venom-and-now-frog-juice-what-will-they-think-of-next.html
A few quotes from the article.
EASY TO MAKE
“Dermorphin is a peptide containing seven amino acid residues, so it is a fairly simple matter to synthesize it using standard biochemical procedures. I doubt that any of the dermorphin that has been found actually came from the South American frog from which it was originally reported. Biochemical supply companies routinely provide these types of chemicals for experimental use, but warn that they are not for medical use, because they have not been approved by U.S. FDA for any medical use.”
DISCOVERED IN THE 1980's
(They first figured out how to test for this stuff in 2012, that's 32 years folks)
(If you believe horsemen first started using this stuff in 2011, I've got some swampland down in Florida for sale)
“It was first described in the 1980s, after isolation from frog skin, and was evaluated experimentally in a number of animal models. I first heard rumors about the use of frog venom in Quarter Horses in early 2011, and it was identified as dermorphin in May 2011.”
IT TAKES A VERY LOW DOSE TO AFFECT THE ANIMAL (Perfect for Horse Racing)
"The fact that a substance is described as being 30-40 times more potent than morphine does not mean that it is more effective than morphine in abolishing pain. It means that it can abolish the pain at a lower dose."
INCREASED LOCOMOTOR ACTIVITY :eek:
“Dermorphin is a substance that has been demonstrated to act as an agonist at the mu-opiate receptor,” Sams says. “Other mu-opiate agonists are morphine, fentanyl, and etorphine. We typically associate these substances with analgesic effects in people and dogs, but they produce a paradoxical effect in horses that results in increased locomotor activity at low doses and low blood concentrations.”
Locomotor skills are those motor skills in which the feet move the body from one place to another.
http://www.equinechronicle.com/health/milkshakes-snake-venom-and-now-frog-juice-what-will-they-think-of-next.html
A few quotes from the article.
EASY TO MAKE
“Dermorphin is a peptide containing seven amino acid residues, so it is a fairly simple matter to synthesize it using standard biochemical procedures. I doubt that any of the dermorphin that has been found actually came from the South American frog from which it was originally reported. Biochemical supply companies routinely provide these types of chemicals for experimental use, but warn that they are not for medical use, because they have not been approved by U.S. FDA for any medical use.”
DISCOVERED IN THE 1980's
(They first figured out how to test for this stuff in 2012, that's 32 years folks)
(If you believe horsemen first started using this stuff in 2011, I've got some swampland down in Florida for sale)
“It was first described in the 1980s, after isolation from frog skin, and was evaluated experimentally in a number of animal models. I first heard rumors about the use of frog venom in Quarter Horses in early 2011, and it was identified as dermorphin in May 2011.”
IT TAKES A VERY LOW DOSE TO AFFECT THE ANIMAL (Perfect for Horse Racing)
"The fact that a substance is described as being 30-40 times more potent than morphine does not mean that it is more effective than morphine in abolishing pain. It means that it can abolish the pain at a lower dose."
INCREASED LOCOMOTOR ACTIVITY :eek:
“Dermorphin is a substance that has been demonstrated to act as an agonist at the mu-opiate receptor,” Sams says. “Other mu-opiate agonists are morphine, fentanyl, and etorphine. We typically associate these substances with analgesic effects in people and dogs, but they produce a paradoxical effect in horses that results in increased locomotor activity at low doses and low blood concentrations.”
Locomotor skills are those motor skills in which the feet move the body from one place to another.